Earn all trophies.
Collect all of only one color of Leech Charms.
Defeat 16 bats in the church.
Combine every type of herb with each other.
Finish the game without combining herbs.
Read all files.
Obtain all weapons.
Put on Team Wesker costume.
Finish the game without using a First-Aid Spray.
Finish the game without using a recovery item (including Green Chemicals).
Kill 50 enemies with the Death Stare at full charge.
Destroy a zombie's legs.
Defeat Mimicry Marcus for the first time only using a knife.
Finish the game on Hard difficulty.
Change into a costume.
Finish the game with rank S.
Finish the game without saving.
Defeat all bosses except Centurion using Rebecca.
Play the piano using Rebecca.
Create a Custom Handgun.
Finish Leech Hunter with rank A.
Finish Leech Hunter with rank E or above.
Defeat all enemies in Leech Hunter.
Defeat an enemy with a knife.
Play Leech Hunter.
Defeat Queen Leech.
Complete the treatment plant.
Obtain all keys and use them all.
Defeat the Proto Tyrant.
Complete the factory.
Fight off the Proto Tyrant.
Complete the laboratory.
Defeat a zombie by stomping on them.
Defeat Infected Bat.
Get picked up by the Infected Bat.
Complete the training facility.
Defeat Mimicry Marcus with a Molotov Cocktail or a Napalm Grenade.
Defeat an enemy by burning them.
Shoot down a Hunter or an Eliminator while they are jump attacking in the air.
Use a Green Chemical.
Attack an enemy to save your partner who is grappling with that enemy.
Try to push something heavy with Rebecca.
Defeat Centurion.
Complete the train.
Defeat an enemy with a critical-hit headshot.
Create a Molotov Cocktail.
Break free of a Cerberus while they are biting you or trying to push you down.
Defeat Stinger.