Earn all trophies.
Finish the game on Very Easy difficulty or higher.
Finish the game on Easy difficulty or higher.
Finish the game on Normal difficulty or higher.
Finish the game on Hard difficulty.
Finish the game with Jill and Chris.
Finish the game in Real Survival mode.
Finish the game in Invisible Enemy mode.
Obtain the Stone & Metal Object using Chris.
Defeat Plant 42 using Chris.
Obtain the "Last Book Vol. 2" using Chris.
Defeat Lisa Trevor using Chris.
Finish the game using Chris.
Defeat a Crimson Head prototype1 using Jill.
Obtain the Helmet Key using Jill.
Defeat Yawn using Jill.
Break into the laboratory using Jill.
Finish the game using Jill.
Die for the first time.
Defeat a zombie.
Burn up a zombie.
Defeat a Hunter.
Save Chris using Rebecca.
Save Jill using Barry.
Save Richard with a serum.
Save Rebecca from a Hunter.
Save Barry from Lisa Trevor.
Save Jill from confinement using Chris.
Save Chris from confinement using Jill.
Finish the game saving Rebecca and Jill using Chris.
Finish the game saving Chris and Barry using Jill.
Finish the game without saving anyone using Chris.
Finish the game without saving anyone using Jill.
Defeat a Crimson Head.
Survive your first encounter with Yawn.
Defeat mother Neptune.
Defeat Black Tiger.
Finish the game in three hours.
Finish the game in five hours.
Finish the game using only your knife (no lighter, Defensive Items, and stomping zombie heads).
Finish the game without saving.
Burn up two zombies at the same time with the lighter.
Obtain all weapons (must load grenade launcher with all shell types).
Obtain all costumes.
Visit all places on all maps.