Earn all trophies.
Obtain all weapons.
Put on Team Wesker costume.
Combine every type of herb with each other.
Defeat Mimicry Marcus for the first time only using a knife.
Defeat 16 bats in the church.
Kill 50 enemies with the Death Stare at full charge.
Finish the game without using a recovery item (including Green Chemicals).
Defeat all bosses except Centurion using Rebecca.
Finish the game with rank S.
Finish the game without combining herbs.
Finish the game without using a First-Aid Spray.
Use a Green Chemical.
Collect all of only one color of Leech Charms.
Finish Leech Hunter with rank E or above.
Finish Leech Hunter with rank A.
Defeat all enemies in Leech Hunter.
Finish the game without saving.
Destroy a zombie's legs.
Play the piano using Rebecca.
Play Leech Hunter.
Complete the treatment plant.
Defeat Queen Leech.
Finish the game on Hard difficulty.
Read all files.
Obtain all keys and use them all.
Defeat the Proto Tyrant.
Try to push something heavy with Rebecca.
Complete the factory.
Fight off the Proto Tyrant.
Complete the laboratory.
Defeat Infected Bat.
Get picked up by the Infected Bat.
Complete the training facility.
Create a Custom Handgun.
Shoot down a Hunter or an Eliminator while they are jump attacking in the air.
Change into a costume.
Defeat a zombie by stomping on them.
Defeat Centurion.
Defeat Mimicry Marcus with a Molotov Cocktail or a Napalm Grenade.
Defeat an enemy by burning them.
Defeat an enemy with a critical-hit headshot.
Complete the train.
Attack an enemy to save your partner who is grappling with that enemy.
Create a Molotov Cocktail.
Defeat Stinger.
Defeat an enemy with a knife.
Break free of a Cerberus while they are biting you or trying to push you down.