Earn all trophies.
Obtain all costumes.
Finish the game in Invisible Enemy mode.
Finish the game saving Rebecca and Jill using Chris.
Save Jill from confinement using Chris.
Save Rebecca from a Hunter.
Save Chris using Rebecca.
Obtain all weapons (must load grenade launcher with all shell types).
Finish the game on Hard difficulty.
Finish the game in Real Survival mode.
Finish the game without saving anyone using Jill.
Finish the game in five hours.
Finish the game using only your knife (no lighter, Defensive Items, and stomping zombie heads).
Finish the game with Jill and Chris.
Finish the game in three hours.
Finish the game without saving.
Finish the game without saving anyone using Chris.
Finish the game using Chris.
Defeat Lisa Trevor using Chris.
Obtain the "Last Book Vol. 2" using Chris.
Defeat Plant 42 using Chris.
Obtain the Stone & Metal Object using Chris.
Finish the game on Very Easy difficulty or higher.
Finish the game on Easy difficulty or higher.
Finish the game on Normal difficulty or higher.
Finish the game saving Chris and Barry using Jill.
Finish the game using Jill.
Visit all places on all maps.
Save Chris from confinement using Jill.
Break into the laboratory using Jill.
Save Barry from Lisa Trevor.
Defeat Black Tiger.
Defeat Yawn using Jill.
Defeat a Hunter.
Obtain the Helmet Key using Jill.
Defeat mother Neptune.
Defeat a Crimson Head prototype1 using Jill.
Survive your first encounter with Yawn.
Die for the first time.
Save Richard with a serum.
Defeat a Crimson Head.
Burn up two zombies at the same time with the lighter.
Burn up a zombie.
Save Jill using Barry.
Defeat a zombie.