Earn all trophies.
Obtain all weapons.
Defeat Mimicry Marcus for the first time only using a knife.
Combine every type of herb with each other.
Put on Team Wesker costume.
Finish the game without using a First-Aid Spray.
Finish the game without using a recovery item (including Green Chemicals).
Finish the game without combining herbs.
Read all files.
Kill 50 enemies with the Death Stare at full charge.
Defeat 16 bats in the church.
Destroy a zombie's legs.
Defeat all bosses except Centurion using Rebecca.
Finish the game with rank S.
Finish the game without saving.
Play the piano using Rebecca.
Change into a costume.
Create a Custom Handgun.
Collect all of only one color of Leech Charms.
Finish Leech Hunter with rank A.
Finish Leech Hunter with rank E or above.
Defeat all enemies in Leech Hunter.
Play Leech Hunter.
Complete the treatment plant.
Defeat Queen Leech.
Finish the game on Hard difficulty.
Obtain all keys and use them all.
Defeat the Proto Tyrant.
Try to push something heavy with Rebecca.
Complete the factory.
Fight off the Proto Tyrant.
Complete the laboratory.
Defeat Infected Bat.
Get picked up by the Infected Bat.
Complete the training facility.
Defeat Mimicry Marcus with a Molotov Cocktail or a Napalm Grenade.
Shoot down a Hunter or an Eliminator while they are jump attacking in the air.
Defeat a zombie by stomping on them.
Use a Green Chemical.
Defeat Centurion.
Defeat an enemy with a knife.
Defeat an enemy by burning them.
Attack an enemy to save your partner who is grappling with that enemy.
Complete the train.
Create a Molotov Cocktail.
Defeat Stinger.
Defeat an enemy with a critical-hit headshot.
Break free of a Cerberus while they are biting you or trying to push you down.