Acquire all trophies.
Clear all Bloody Palace stages with all characters.
Clear all Bloody Palace stages with Trish.
Clear all Bloody Palace Mode stages with an S ranking.
Clear all Bloody Palace stages with Lady.
Clear all Bloody Palace stages with Vergil.
Defeat 10,000 enemies.
Defeat Dante in the Bloody Palace without taking any damage.
Clear all Bloody Palace stages with Dante.
Clear the Bloody Palace in Turbo Mode.
Clear all game modes.
Clear all Bloody Palace stages with Nero.
Clear the Bloody Palace within 2 hours.
Clear the game with Vergil.
Clear all missions in Hell and Hell Mode.
Clear all missions in Heaven or Hell Mode.
Clear all missions in Legendary Dark Knight Mode.
Clear all missions in Legendary Dark Knight Mode with an S Ranking.
Clear all missions in Dante Must Die Mode.
Clear all missions in Dante Must Die Mode with an S ranking.
Defeat 10 enemies within 1 second.
Defeat The Savior with an SSS ranking in Son of Sparda Mode or higher.
Clear the game with Lady and Trish.
Clear all missions in Son of Sparda Mode with an S ranking.
Clear all missions in Son of Sparda Mode.
Defeat Berial with an SSS ranking in Son of Sparda Mode or higher.
Defeat Dante with an SSS ranking in Son of Sparda Mode or higher.
Defeat Angelo Agnus with an SSS ranking in Son of Sparda Mode or higher.
Defeat Angelo Credo with an SSS ranking in Son of Sparda Mode or higher.
Defeat Echidna with an SSS ranking in Son of Sparda Mode or higher.
Defeat Bael or Dagon with an SSS ranking in Son of Sparda Mode or higher.
Clear all missions in Devil Hunter Mode with an S ranking.
Clear all missions in Human Mode with an S ranking.
Clear all missions in Human Mode.
Acquire all of Dante's skills.
Acquire all of Nero's skills.
Defeat 1,000 enemies.
Clear all missions in Devil Hunter Mode.
Clear all secret missions.
Complete a Stylish Rank SSS (Smokin' Sick Style!!!) combo.
Complete a Stylish Rank SS (Smokin' Style!!) combo.
Defeat 100 enemies.
Complete a Stylish Rank S (Smokin'!) combo.