The player has completed the game on the Hard difficulty setting

The player has defeated Atlas

The player has become a Big Daddy

Acquire all upgrades for all weapons

Successfully invent at least 100 items

The player has either Harvested or Rescued every possible Little Sister

Fully upgrade five weapons

Collect or Invent 58 Tonics in the Physical, Engineering and Combat tracks

Purchased every slot in all four Plasmid and Tonic tracks

The player has broken Fontaine's mind control

The player has entered Sander Cohen's personal quarters

The player has taken a picture of Sander Cohen's corpse

Fully upgrade four weapons

The player has defeated Andrew Ryan

Fully research the Bouncer

Max out all possible research

The player has fully upgraded three weapons

The player has purchased every slot in one of the Plasmid or Tonic tracks

Hit the jackpot at a slot machine

The player has completed Sander Cohen's great masterpiece

Fully research the Little Sister

Take at least one photo in every research group

The player has fully upgraded two weapons

The player has fully researched the Spider Splicer

The player has successfully invented all possible ammo types

The player has restored the forests of Arcadia

The player has fully upgraded one weapon

Fully research the Rosie

Fully research the Houdini Splicer

The player has fully researched the Thuggish Splicer

The player has successfully invented at least one item

The player has acquired at least one weapon upgrade

The player has defeated Peach Wilkins

Fully research the Nitro Splicer

The player has fully researched the Leadhead Splicer

The player has taken a Research Photo of the highest grade

The player has taken at least one Research Photo of a Splicer

The player has successfully completed 50 hacks

The player has purchased one slot in any Plasmid or Tonic track

The player has defeated the crazed Dr. Steinman

The player has successfully hacked a safe

The player has successfully hacked a security camera

The player has successfully hacked a turret

The player has successfully hacked a vending machine

The player has performed at least one successful hack

The player has successfully hacked a security bot

The player has successfully completed the Welcome To Rapture Level

The player has shocked an enemy in the water